Báo cáo khóa học: New substrate analogues of human serotonin N-acetyltransferase produce in situ speciﬁc and potent inhibitors

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Báo cáo khóa học: New substrate analogues of human serotonin N-acetyltransferase produce in situ speciﬁc and potent inhibitors

Ánh Thơ 52 11 pdf

Melatonin is synthesized by an enzymatic pathway, in which arylalkylamine (serotonin)N-acetyltransferase cata-lyzes the rate-limiting step. Aprevious study [Khalil, E.M., DeAngelis, J., Ishii,M.&Cole, P.A. (1999)Proc.NatlAcad. Sci. USA 96, 12418–12423] reported the discovery of bromoacetyltryptamine (BAT), a new type of inhibitor of this enzyme. This compound is the precursor of a potent bifunctional inhibitor (analogue of the transition state), capable of interfering with both the substrate and the cosubstrate binding sites. .

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Báo cáo khóa học: New substrate analogues of human serotonin N-acetyltransferase produce in situ speciﬁc and potent inhibitors

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Đang chuẩn bị liên kết để tải về tài liệu: Báo cáo khóa học: New substrate analogues of human serotonin N-acetyltransferase produce in situ speciﬁc and potent inhibitors

Báo cáo khoa học: "Recently published papers: Out with the old and in with the new … then something new for the old"

báo cáo khoa học: "Virtual reality and physical rehabilitation: a new toy or a new research and rehabilitation tool?"

báo cáo khoa học:" Editor's note: new facial nerve section and new editorial board member"

Báo cáo toán học: "A new proof of the Szegö limit theorem and new results for Toeplitz operators with discontinuous symbol "

Báo cáo y học: " Respiratory Research: a new multidisciplinary journal for a new age "

Báo cáo y học: " Recently published papers: New evidence for old debates, new drugs and some timely reminders"

Báo cáo y học: " A review of 2004, and with the new year comes a new look"

Báo cáo y học: "The journal ‘chiropractic & osteopathy’ changes its title to ‘chiropractic & manual therapies’. a new name, a new era"

báo cáo sinh học:" New Role, New Country: introducing US physician assistants to Scotland"

báo cáo hóa học: " Virtual reality and physical rehabilitation: a new toy or a new research and rehabilitation tool?"

Đang chuẩn bị liên kết để tải về tài liệu:
Báo cáo khóa học: New substrate analogues of human serotonin N-acetyltransferase produce in situ speciﬁc and potent inhibitors