Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Public perception of stem cell and genomics research | Lensch Genome Medicine 2011 3 44 http content 3 7 44 w Genome Medicine MUSINGS L__ Public perception of stem cell and genomics research M William Lensch1 2 3 The importance of stem cells and genomics for translational research The confluence of human stem cell and genome research is laden with opportunity. Information gleaned from the Human Genome Project HGP has already done much to expand our understanding of human biology and disease reviewed in 1 . The same can be said of human pluripotent stem cell hPSC research involving human embryonic stem cells hESCs and induced pluripotent stem cells iPSCs . For translational stem cell research especially where it involves reprogramming of mature cells to make iPSCs and their subsequent directed differentiation to other clinically useful cells and tissues obtaining a deeper understanding of the role of genomewide transcriptional and epigenetic alterations will be invaluable. Taking the stem cells and genomics relationship to the next level seems like a good idea. The availability of hPSCs has accelerated research into the underpinnings of development and genetic disease. Such cells provide abundant starting material for a range of in vitro studies for example i tissues representing hard-to-access anatomical locations ii a wide variety of genetic backgrounds iii disease models using iPSCs derived from patients for whom the investigator has access to a detailed clinical history and iv the opportunity to monitor tissue genesis at its earliest stages in health and disease alike reviewed in 2 . The current frequency of papers describing novel hPSC-based model systems of human diseases reminds me of the heyday of gene mapping identification studies in the late 1980s and early 1990s. Back then it was commonplace to pick up the latest issue of nearly any leading journal and find papers describing disease-causing genes. It felt like a human genetics renaissance. Correspondence .
