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Báo cáo y học: " Lymphocytic colitis presenting as difficult diarrhoea in an African woman: a case report and review of the literature"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Lymphocytic colitis presenting as difficult diarrhoea in an African woman: a case report and review of the literature | Ekrikpo et al. Journal of Medical Case Reports 2010 4 31 http www.jmedicalcasereports.eom content 4 1 31 jAg JOURNALOF medical ÌỤr case REPORTS CASE REPORT Open Access Lymphocytic colitis presenting as difficult diarrhoea in an African woman a case report and review of the literature Udeme E Ekrikpo1 Jesse A Otegbayo1 Abideen O Oluwasola2 Abstract Introduction Lymphocytic colitis is an uncommon intestinal disorder that presents with chronic diarrhoea. It is treatable but in the developing world its diagnosis may often prove difficult. Data and reports of this condition in Africa are scarce because most medical centres lack a functional gastrointestinal endoscopy unit that would aid in the diagnosis. Case presentation We present the case of a 53-year-old Nigerian woman with pathogen-negative chronic diarrhoea and a family history of chronic diarrhoea. She responded well to treatment after colonoscopy and colonic biopsy successfully diagnosed her illness. Conclusion Referral of patients with pathogen-negative chronic diarrhoea to medical centres that have facilities for colonoscopy and biopsy is important in the developing world. Introduction In the developing world where there is scarcity of facilities for endoscopy in many medical centres patients presenting with chronic or recurrent diarrhoea for which no infective metabolic or mechanical cause is found are usually thought to have the diarrhoeal type of irritable bowel syndrome and therefore managed empirically as such. Lymphocytic colitis and collagenous colitis make up a group of uncommon large bowel inflammatory conditions called microscopic colitis. It is yet to be fully ascertained if these two clinical conditions are separate entities albeit with similar clinical presentation or if they are clinical manifestations of a spectrum of clinical conditions 1 . The implication of certain drugs such as ranitidine ticlopidine flutamide carbamazepine sertraline paroxetine simvastatin and Cyclo 3 Fort in the .