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báo cáo hóa học:" Cartilage contact pressure elevations in dysplastic hips: a chronic overload model"

Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học quốc tế đề tài : Cartilage contact pressure elevations in dysplastic hips: a chronic overload model | Journal of Orthopaedic Surgery and Research BioMed Central Research article Cartilage contact pressure elevations in dysplastic hips a chronic overload model Mary E Russell2 Kiran H Shivanna2 Nicole M Grosland2 1 and Douglas R Pedersen 1 2 Open Access Address Department of Orthopaedics and Rehabilitation University of Iowa Iowa City Iowa and 2Department of Biomedical Engineering University of Iowa Iowa City Iowa USA Email Mary E Russell - Mary.E.Russell@dmu.edu Kiran H Shivanna - kshivann@engineering.uiowa.edu Nicole M Grosland - Nicole- Grosland@uiowa.edu Douglas R Pedersen - doug-pedersen@uiowa.edu Corresponding author Published 03 October 2006 Received 17 March 2006 Journal of Orthopaedic Surgery and Research 2006 1 6 doi l0.ll86 I749-799X-I-6 Accepted 03 October 2006 This article is available from http www.josr-online.com content 1 1 6 2006 Russell et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Developmental dysplasia of the hip DDH is a condition in which bone growth irregularities subject articular cartilage to higher mechanical stresses increase susceptibility to subluxation and elevate the risk of early osteoarthritis. Study objectives were to calculate threedimensional cartilage contact stresses and to examine increases of accumulated pressure exposure over a gait cycle that may initiate the osteoarthritic process in the human hip in the absence of trauma or surgical intervention. Methods Patient-specific non-linear contact finite element models constructed from computed tomography arthrograms using a custom-built meshing program were subjected to normal gait cycle loads. Results Peak contact pressures for dysplastic and asymptomatic hips ranged from 3.56 - 9.88 MPa. Spatially .