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Báo cáo hóa học: " Genetic diversity and silencing suppression effects of Rice yellow mottle virus and the P1 protein"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Genetic diversity and silencing suppression effects of Rice yellow mottle virus and the P1 protein | Virology Journal BioMed Central Research Genetic diversity and silencing suppression effects of Rice yellow mottle virus and the PI protein Christelle Siré1 Martine Bangratz-Reyser1 Denis Fargette2 and Christophe Brugidou 1 Open Access Address 1Institut de Recherche pour le Développement IRD UMR LGDP 34394 Montpellier Cedex 5 France and 2Institut de Recherche pour le Développement IRD UMR RPB 34394 Montpellier Cedex 5 France Email Christelle Siré - sire.christelle@gmail.com Martine Bangratz-Reyser-martine.bangratz@mpl.ird.fr Denis Fargette - denis.fargette@mpl.ird.fr Christophe Brugidou - christophe.brugidou@mpl.ird.fr Corresponding author Published 30 April 2008 Received 10 December 2007 Accepted 30 April 2008 Virologyjournal 2008 5 55 doi 10.1186 1743-422X-5-55 This article is available from http www.virologyj.cOm content 5 1 55 2008 Siré et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background PTGS post-transcriptional gene silencing is used to counter pathogenic invasions particularly viruses. In return many plant viruses produce proteins which suppress silencing directed against their RNA. The diversity of silencing suppression at the species level in natural hosts is unknown. Results We investigated the functional diversity of silencing suppression among isolates of the African RYMV Rice yellow mottle virus in rice. The RYMV-P1 protein is responsible for cell-to-cell movement and is a silencing suppressor. Transgenic gus-silencing rice lines were used to investigate intra-specific and serogroup silencing suppression diversity at two different levels that of the virion and the P1 silencing suppressor protein. Our data provide evidence that silencing suppression is a universal phenomenon for RYMV .