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báo cáo hóa học: " Comparing the accuracy of the three popular clinical dehydration scales in children with diarrhea"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Comparing the accuracy of the three popular clinical dehydration scales in children with diarrhea | Pringle et al. International Journal of Emergency Medicine 2011 4 58 http www.intjem.eom content 4 1 58 o International Journal of Emergency Medicine a SpringerOpen Journal ORIGINAL RESEARCH Open Access Comparing the accuracy of the three popular clinical dehydration scales in children with diarrhea Kimberly Pringle1 6 Sachita P Shah1 Irenee Umulisa2 Richard B Mark Munyaneza2 Jean Marie Dushimiyimana3 Katrina Stegmann3 Juvenal Musavuli4 Protegene Ngabitsinze4 Sara Stulac5 and Adam C Levine1 5 Abstract Background Dehydration due to acute gastroenteritis is one of the leading causes of mortality in children worldwide. The World Health Organization WHO scale the Gorelick scale and the Clinical Dehydration Scale CDS were created to estimate percentage dehydration in children with gastroenteritis based on clinical signs. Of these only the CDS has been prospectively validated against a valid gold standard though never in low- and middleincome countries. The purpose of this study is to determine whether these clinical scales can accurately assess dehydration status in children when performed by nurses or general physicians in a low-income country. Methods We prospectively enrolled a non-consecutive sample of children presenting to three Rwandan hospitals with diarrhea and or vomiting. A health care provider documented clinical signs on arrival and weighed the patient using a standard scale. Once admitted the patient received rehydration according to standard hospital protocol and was weighed again at hospital discharge. Receiver operating characteristic ROC curves were created for each of the three scales compared to the gold standard percent weight change with rehydration. Sensitivity specificity and likelihood ratios were calculated based on the best cutoff points of the ROC curves. Results We enrolled 73 children and 49 children met eligibility criteria. Based on our gold standard the children had a mean percent dehydration of 5 on arrival. The WHO scale Gorelick scale