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Enzyme Nomenclature and Classification

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Enzyme Nomenclature and Classification • Enzymes are commonly named by adding a suffix "-ase" to the root name of the substrate molecule it is acting upon. For example, Lipase catalyzes the hydrolysis of a lipid triglyceride. Sucrase catalyzes | Enzyme Nomenclature and Classification Enzymes are commonly named by adding a suffix "-ase" to the root name of the substrate molecule it is acting upon. For example, Lipase catalyzes the hydrolysis of a lipid triglyceride. Sucrase catalyzes the hydrolysis of sucrose into glucose and fructose. A few enzymes discovered before this naming system was devised are known by common names. Examples are pepsin, trypsin, and chymotrypsin which catalyzes the hydrolysis of proteins. Enzyme Nomenclature and Classification The latest systematic nomenclature system known as the International Enzyme Commission (IEC) system is based upon the type of reaction catalyzed. There are six broad groups of enzymes in this system as shown in table Enzyme Nomenclature and Classification Enzyme Nomenclature and Classification Class 1. Oxidoreductases. This class belong all enzymes catalysing oxidoreduction reactions The substrate that is oxidized is regarded as hydrogen donor The systematic name is based on donor:acceptor oxidoreductase. The common name will be dehydrogenase, an alternative, reductase can be used. Oxidase is only used in cases where O2 is the acceptor Enzyme Nomenclature and Classification Class 2. Transferases. Transferases are enzymes transferring a group e.g. a methyl group or a glycosyl group, from one compound (generally regarded as donor) to another compound (generally regarded as acceptor). The systematic names are formed according to the scheme donor:acceptor grouptransferase. The common names are normally formed according to acceptor grouptransferase or donor grouptransferase. In many cases, the donor is a cofactor (coenzyme) charged with the group to be transferred Enzyme Nomenclature and Classification Class 3. Hydrolases. These enzymes catalyse the hydrolytic cleavage of C-O, C-N, C-C and some other bonds, including phosphoric anhydride bonds. Although the systematic name always includes hydrolase, the common name is, in many cases, formed by the name of the . | Enzyme Nomenclature and Classification Enzymes are commonly named by adding a suffix "-ase" to the root name of the substrate molecule it is acting upon. For example, Lipase catalyzes the hydrolysis of a lipid triglyceride. Sucrase catalyzes the hydrolysis of sucrose into glucose and fructose. A few enzymes discovered before this naming system was devised are known by common names. Examples are pepsin, trypsin, and chymotrypsin which catalyzes the hydrolysis of proteins. Enzyme Nomenclature and Classification The latest systematic nomenclature system known as the International Enzyme Commission (IEC) system is based upon the type of reaction catalyzed. There are six broad groups of enzymes in this system as shown in table Enzyme Nomenclature and Classification Enzyme Nomenclature and Classification Class 1. Oxidoreductases. This class belong all enzymes catalysing oxidoreduction reactions The substrate that is oxidized is regarded as hydrogen donor The systematic name is based on .