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RNA Interference Technology FROM BASIC SCIENCE TO DRUG DEVELOPMENT

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It has been a privilege to watch the growth of RNA interference technology over the last ten years. Starting with a mixture of curiosity and chagrin, the field has grown into a substantial enterprise which impacts (and utilizes resources from) virtually every field of biomedical research. Research in RNAi derives from a set of apparently unconnected observations: strange pigment patterns in plants, unexpected failures and successes in antisense and overexpression studies, small regulatory RNAs in bacteria. If there is an underlying and recurring scientific lesson, it has been: “Pursue the unexpected.” Basic and applied research each advance as a consequence of this pursuit; certainly this has been no.

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RNA virus interference via CRISPR/Cas13a system in plants

CRISPR-Cas13d mediates robust RNA virus interference in plants

Đồ án tốt nghiệp: Ứng dụng thử nghiệm công nghệ RNA interference vào nghiên cứu chuyển đổi giới tính tôm càng xanh Macrobrachium rosenbergii (De Man, 1879)

Development of an improved RNA interference vector system for Agrobacterium-mediated plant transformation

Knockdown of five trehalase genes using RNA interference regulates the gene expression of the chitin biosynthesis pathway in Tribolium castaneum

Development of an efficient RNA interference method by feeding for the microcrustacean Daphnia

Lentivirus-mediated short hairpin RNA interference targeting TNF-alpha in macrophages inhibits particle-induced inflammation and osteolysis in vitro and in vivo

RNA Interference Technology FROM BASIC SCIENCE TO DRUG DEVELOPMENT

RNA interference of the Hemonchus contortus Astacin-like MTP Gene by the soaking method

In silico analysis of fungal small RNA accumulation reveals putative plant mRNA targets in the symbiosis between an arbuscular mycorrhizal fungus and its host plant
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