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Early and long term results of mitral valve repair for mitral regurgitation due to isolated posterior leaflet prolapse

Objectives: To evaluate the long-term results of mitral valve repair in patients with mitral regurgitation caused by isolated posterior leaflet prolapse at Danang Hospital. Subjects and methods: A retrospective, descriptive study combined with a prospective study. Thirty two patients with chronic severe mitral regurgitation due to isolated posterior leaflet prolapse were treated by new surgical techniques in Danang Hospital from February 2010 to October 2017. | Journal of military pharmaco-medicine no7-2018 EARLY AND LONG-TERM RESULTS OF MITRAL VALVE REPAIR FOR MITRAL REGURGITATION DUE TO ISOLATED POSTERIOR LEAFLET PROLAPSE Tran Ngoc Vu*; Le Ngoc Thanh** SUMMARY Objectives: To evaluate the long-term results of mitral valve repair in patients with mitral regurgitation caused by isolated posterior leaflet prolapse at Danang Hospital. Subjects and methods: A retrospective, descriptive study combined with a prospective study. Thirty two patients with chronic severe mitral regurgitation due to isolated posterior leaflet prolapse were treated by new surgical techniques in Danang Hospital from February 2010 to October 2017. Preoperative, pre-discharge and follow-up findings were recorded. Postoperative echocardiography was performed in all patients at predischarge and during clinical follow-up. Late survival and freedom from adverse events including hemorrhage, endocarditis, reoperation, and residual severe mitral regurgitation were estimated by using the Kaplan-Meier survival analysis. Results: Ages ranged from 12 to 68 years (mean 43.06 ± 15.78 years). According to New York Heart Association (NYHA) functional classification: 3.12% (1/32) of patients were in class I; 90.63% (29/32) were in class II; 6.25% (2/32) were in class III, and no patient was in class IV; 32 patients (100%) had severe mitral valve regurgitation (3+). Twentysix patients were treated by triangular resection of posterior leaflet; five patients by chordal replacement and one patient by both techniques. Echocardiography was carried out in all patients before discharged from hospital; 96.88% of patients had no or mild regurgitation, and 3.12% of patients had moderate regurgitation (2+), no one had severe regurgitation; no inhospital mortality. Late mortality occurred in only one patient at 3 months after discharge because of severe heart failure. The mean follow-up time of patients was 36.44 ± 26.09 months (from 3 to 94 months), all the 31 surviving patients