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Synthesis of metal nanoparticles using Heliconia rostrata leaf extract and their antiproliferative and apoptotic property

The silver and gold nanoparticles were biosynthesized using leaves of a pharmacologically important plant Heliconia rostrata. | Synthesis of metal nanoparticles using Heliconia rostrata leaf extract and their antiproliferative and apoptotic property Current Chemistry Letters 7 2018 65 72 Contents lists available at GrowingScience Current Chemistry Letters homepage www.GrowingScience.com Synthesis of metal nanoparticles using Heliconia rostrata leaf extract and their antiproliferative and apoptotic property Lingappa Malleshaa Guruswamy Vinaya and Nanjappagowda Dharmappa Rekhab a PG Department of Chemistry JSS College of Arts Commerce and Science B. N. Road Mysuru-25 India b PG Department of Biotechnology JSS College of Arts Commerce and Science B. N. Road Mysuru-25 India CHRONICLE ABSTRACT Article history The silver and gold nanoparticles were biosynthesized using leaves of a pharmacologically Received December 22 2017 important plant Heliconia rostrata. A rapid eco-friendly cost-effective and one-step process Received in revised form of synthesis has been achieved thus produced nanoparticles were characterized by UV visible April 12 2018 FT-IR XRD and TEM spectral studies. Further newly synthesized nanoparticles were used to Accepted April 12 2018 study the induction of apoptotic activity on EAT cells. These two type of nanoparticles showed Available online antiproliferative and apoptotic property in mice model. The outcome of this study could be April 12 2018 useful for the development of value added products from indigenous medicinal plants which Keywords has biomedical applications. Heliconia rostrate Nanoparticles Anti-proliferative activity 2018 Growing Science Ltd. All rights reserved. 1. Introduction The growth of green biosynthesis for the production of nanoparticles is evolving into an important branch of nanotechnology.1 Numerous methodologies are developed to synthesize noble metal nanoparticles of particular shape and size depending on specific requirements. Biosynthesis of nanoparticles has an emerging highlight of the intersection of nanotechnology and biotechnology which .