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A review of machine learning methods to predict the solubility of overexpressed recombinant proteins in Escherichia coli

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Over the last 20 years in biotechnology, the production of recombinant proteins has been a crucial bioprocess in both biopharmaceutical and research arena in terms of human health, scientific impact and economic volume. Although logical strategies of genetic engineering have been established, protein overexpression is still an art. |

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