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Development of Green protocols for the synthesis of 1H-benzo[d]imidazolo aryl amide derivatives and evaluation of their biological activity

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Benzimidazole scaffold containing chemical derivatives show superior biological activity. In view of this, we synthesized a combination of benzimidazole and aryl amides. The target compounds (6a-j) were synthesized using ethyl 3-iodobenzoate and benzimidazole as starting materials under microwave conditions. The synthesized compounds were screened against gram (+ve) and gram (-ve) bacteria as well as for their anti-oxidant activity. Compound 6a was proved to be most active in inhibiting the DPPH free radical. |

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