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SARS-CoV-2 triggers inflammatory and cell death in experimental infection by activating human cells caspases

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Apoptosis is a process that occurs in programmed physiological and nonphysiological cell death. In morphological aspect, among apoptosis products, cell shrinkage, subsequent to the degeneration of the nucleus characterized by condensation of chromatin, followed by the nuclear membrane disappearance. In particular, apoptosis modulation in SARS-CoV infection seems to be directly associated with specific cell-type interactions, which can significantly influence the manifestations resulting from the pathology. Therefore, it is noted the need for studies that promote debates about the modulation of apoptosis in animals and humans, infected by SARS-CoV. |