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Seroprevalence of hepatitis B and hepatitis C viral infections in thalassemia patients undergoing multiple blood transfusions in a Tertiary Care Hospital

Thalassemia is one of commonest hereditary disease worldwide, prevalent in humid climates and affects all races. The Transfusion Dependent Thalassemias require regular blood transfusion to survive. The thalassemia patients require lifelong blood transfusion on regular basis- usually administered every 2 to 5 weeks. Due to regular blood transfusion, transfusion transmitted disease e.g. Hepatitis B Virus (HBV), Hepatitis C virus (HCV) and Human Immunodeficiency Virus (HIV) infections can occur. | Int.J.Curr.Microbiol.App.Sci 2021 10 03 1339-1346 International Journal of Current Microbiology and Applied Sciences ISSN 2319-7706 Volume 10 Number 03 2021 Journal homepage http www.ijcmas.com Original Research Article https doi.org 10.20546 ijcmas.2021.1003.164 Seroprevalence of Hepatitis B and Hepatitis C Viral Infections in Thalassemia Patients Undergoing Multiple Blood Transfusions in a Tertiary Care Hospital Anupriya Yadav Rameshwari Bithu Manju Yadav and Rakesh K. Maheshwari Department of Microbiology Sawai Man Singh Medical College and Attached Hospitals Jaipur Rajasthan India Corresponding author ABSTRACT Thalassemia is one of commonest hereditary disease worldwide prevalent in humid climates and affects all races. The Transfusion Dependent Thalassemias require regular blood transfusion to survive. The thalassemia patients require lifelong blood transfusion on regular Keywords basis- usually administered every 2 to 5 weeks. Due to regular blood transfusion transfusion Hepatitis B and transmitted disease e.g. Hepatitis B Virus HBV Hepatitis C virus HCV and Human Hepatitis C Viral Immunodeficiency Virus HIV infections can occur. Aim of the study is to evaluate the Infections prevalence of Hepatitis B amp C viral infections transmitted by blood transfusion among Seroprevalence thalassemia patients. Observational study conducted over a period of one year a total of 118 thalassemia patients were studied. Patients were screened for Hepatitis B and Hepatitis C viral Article Info infections by rapid test kits and the conformation was done by ELISA. Out of 118 thalassemia Accepted patients 74 62.7 were male and 44 37.3 were females. Out of them 36 30.5 patients 12 February 2021 were anti HCV reactive and none was reactive for HBsAg. Multi transfused patients must be Available Online regularly tested and monitored to ensure safe blood transfusion practices. The patients should 10 March 2021 be encouraged to stick to one thalassemia management centre. Stringent .