Đang chuẩn bị liên kết để tải về tài liệu:
Isogenic mice exhibit sexually-dimorphic DNA methylation patterns across multiple tissues

Không đóng trình duyệt đến khi xuất hiện nút TẢI XUỐNG Tải xuống

Cytosine methylation is a stable epigenetic modification of DNA that plays an important role in both normal physiology and disease. Most diseases exhibit some degree of sexual dimorphism, but the extent to which epigenetic states are influenced by sex is understudied and poorly understood. To address this deficit we studied DNA methylation patterns across multiple reduced representation bisulphite sequencing datasets (from liver, heart, brain, muscle and spleen) derived from isogenic male and female mice. |