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Biotechnology and food sciences, Design and synthesis of novel pyrimidine analogs as anti tubercular agents targeting thymidine kinase domain

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In silico studies reports that their physicochemical, ADMET and druglikeness properties were found to be in standard limit, which infers that, these compounds may not have problems with oral bioavailability. Molecular docking studies showed that the pyrimidines have better enzyme inhibitory activity onTMPKmt. |

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