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The employment of a conformal polydopamine thin layer reduces the cytotoxicity of silver nanoparticles

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Silver nanoparticles (AgNPs) with their unique properties represent great promise in biological applications. However, the high toxicity of AgNPs still remains a major bottleneck and hinders their basic usage. In the present study, to improve the cytotoxicity of AgNPs, a thin layer of polydopamine (PDOP) was proposed as shell material. For this, the as-prepared citrate-stabilized AgNPs were dispersed in dopamine solution under alkaline conditions. The thickness of the PDOP layer could be manipulated simply by tuning the polymerization time. |

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