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Báo cáo y học: "Cognitive function among hemodialysis patients in Japan"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Cognitive function among hemodialysis patients in Japan. | Odagiri et al. Annals of General Psychiatry 2011 10 20 http www.annals-general-psychiatry.eom content 10 1 20 ANNALS OF GENERAL PSYCHIATRY PRIMARY RESEARCH Open Access Cognitive function among hemodialysis patients in Japan z z-s I 1 1 1 2 2 3 Gen Odagiri Norio Sugawara Atsuhiro Kikuchi Ippei Takahashi Takashi Umeda Hisao Saitoh Norio Yasui-Furukori1 and Sunao Kaneko1 Abstract Background Over 290 000 patients are undergoing hemodialysis HD in Japan. With old age the odds of undergoing HD treatment sharply increase as does the prevalence of cognitive impairment. The aim of the present work was to assess cognitive impairment in HD patients and its relation to clinical characteristics. Methods Using a cross-sectional design we administered the Mini-Mental State Examination MMSE to 154 HD outpatients and 852 participants from the Iwaki Health Promotion Project 2010 representing the general population. Results The prevalence of cognitive impairment based on the MMSE was 18.8 in HD patients. HD patients showed a higher prevalence of cognitive impairment in older groups 50 years and older . In a logistic regression model with age gender and amount of education as covariates undergoing HD was a significant independent factor OR 2.28 95 CI 1.33 to 3.94 associated with a lower MMSE score. Among HD patients we found that level of education was associated with MMSE score. Conclusions There is a high prevalence of cognitive impairment among HD patients that has adverse implications for hospitalization and shortens their life expectancy. HD treatment was an independent risk factor for cognitive impairment. Clinicians should carefully monitor and treat cognitive impairment in HD patients. Further studies are required to determine the reasons for cognitive impairment in HD patients. Introduction Advances in medical technology and improvements in public health have brought about a progressive increase in the population undergoing hemodialysis HD . Over 290 000 patients receive HD .