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Báo cáo y học: "Functional magnetic resonance imaging findings in fibromyalgia"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Functional magnetic resonance imaging findings in fibromyalgia. | Available online http arthritis-research.eom content 8 6 224 Review Biology and therapy of fibromyalgia Functional magnetic resonance imaging findings in fibromyalgia David A Williams1 2 and Richard H Gracely1 3 1Chronic Pain and Fatigue Research Center Department of Internal Medicine Division of Rheumatology University of Michigan Health System University of Michigan Ann Arbor MI USA 2Department of Psychiatry University of Michigan Health System University of Michigan Ann Arbor MI USA 3Department of Neurology University of Michigan Health System University of Michigan and Ann Arbor VAMC Ann Arbor MI USA Corresponding author Richard H Gracely rgracely@med.umich.edu Published 17 January 2007 This article is online at http arthritis-research.com content 8 6 224 2006 BioMed Central Ltd Arthritis Research Therapy 2006 8 224 doi 10.1186 ar2094 Abstract Techniques in neuroimaging such as functional magnetic resonance imaging fMRI have helped to provide insights into the role of supraspinal mechanisms in pain perception. This review focuses on studies that have applied fMRI in an attempt to gain a better understanding of the mechanisms involved in the processing of pain associated with fibromyalgia. This article provides an overview of the nociceptive system as it functions normally reviews functional brain imaging methods and integrates the existing literature utilizing fMRI to study central pain mechanisms in fibromyalgia. Introduction Fibromyalgia FM affects six to ten million Americans 1 and the incidence is estimated to be one to four percent in the general population 2 . The symptoms associated with FM significantly affect patients quality of life 3 and can lead to extensive use of health care services 4 . Fibromyalgia is experienced as a chronic widespread pain condition accompanied by fatigue tenderness sleep disturbance decrements in physical functioning and disruptions in psychological functioning for example memory problems diminished mental clarity mood .