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Báo cáo khoa học: " Multidisciplinary approach of early breast cancer: The biology applied to radiation oncology"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: " Multidisciplinary approach of early breast cancer: The biology applied to radiation oncology. | Bourgier et al. Radiation Oncology 2010 5 2 http www.ro-journal.eom content 5 1 2 RADIATION ONCOLOGY REVIEW Open Access Multidisciplinary approach of early breast cancer The biology applied to radiation oncology Céline Bourgier1 Mahmut Ozsahin2 David Azria3 Abstract Early breast cancer treatment is based on a multimodality approach with the application of clinical and histological prognostic factors to determine locoregional and systemic treatments. The entire scientific community is strongly involved in the management of this disease radiologists for screening and early diagnosis gynecologists surgical oncologists and radiation oncologists for locoregional treatment pathologists and biologists for personalized characterization genetic counselors for BRCA mutation history and medical oncologists for systemic therapies. Recently new biological tools have established various prognostic subsets of breast cancer and developed predictive markers for miscellaneous treatments. The aim of this article is to highlight the contribution of biological tools in the locoregional management of early breast cancer. Introduction Breast cancer is the most common female cancer in France with increasing incidence over the last two decades and with decreasing mortality 1 . Systematic screening can detects early breast cancers that are potentially curable. All physicians are implicated in the management of early breast cancer radiologists for screening and diagnosis gynecologists breast surgeons and radiation oncologists for locoregional treatment pathologists and biologists for individualized tumor characterization genetic counselors for BRCA mutation history and medical oncologists for systemic therapies. Recently biological tools have identified different prognostic subsets of breast cancers and may predict treatment efficacy 2-8 . This review highlights the contribution of biological tools in a multidisciplinary approach especially in locor-egional treatment of early breast cancers.