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Báo cáo y học: "Knee meniscal extrusion in a largely non-osteoarthritic cohort: association with greater loss of cartilage volume"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Knee meniscal extrusion in a largely non-osteoarthritic cohort: association with greater loss of cartilage volume. | Available online http arthritis-research.eom content 9 2 R21 Open Access Research article Knee meniscal extrusion in a largely non-osteoarthritic cohort association with greater loss of cartilage volume Changhai Ding1 Johanne Martel-Pelletier2 Jean-Pierre Pelletier2 Frangois Abram3 Jean- Pierre Raynauld2 Flavia Cicuttini4 and Graeme Jones1 1Menzies Research Institute University of Tasmania 199 Macquarie Street Hobart 7000 Australia 2Osteoarthritis Research Unit University of Montreal Hospital Centre Notre-Dame Hospital 1560 Sherbrooke St East Montreal H2L 4M1 Canada 3ArthroVision Inc. 1871 rue Sherbrooke Est Montreal H2K 1B6 Canada 4Department of Epidemiology and Preventive Medicine Monash University Medical School Commercial Road Melbourne 3181 Australia Corresponding author Changhai Ding chding@utas.edu.au Received 31 Oct 2006 Revisions requested 12 Jan 2007 Revisions received 30 Jan 2007 Accepted 2 Mar 2007 Published 2 Mar 2007 Arthritis Research Therapy 2007 9 R21 doi 10.1186 ar2132 This article is online at http arthritis-research.com content 9 2 R21 2007 Ding et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract We conducted a longitudinal study duration 2 years including 294 individuals mean age 45 years 58 female in order to examine associations between meniscal extrusion knee structure radiographic changes and risk factors for osteoarthritis OA in a largely non-osteoarthritic cohort. Meniscal extrusion tibiofemoral cartilage defect score and cartilage volume and tibial plateau bone area were determined using T1-weighted fat-saturated magnetic resonance imaging. At baseline the presence of medial meniscal extrusion was significantly associated with body mass index odds ratio OR per kg m2 1.13 95 confidence