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Báo cáo khoa học: "Impact of coccidial infection on vaccine- and vvIBDV in lymphoid tissues of SPF chickens as detected by RT-PCR"

Tuyển tập các báo cáo nghiên cứu về bệnh học thý y được đăng trên tạp chí Acta Veterinaria Scandinavica cung cấp cho các bạn kiến thức về bệnh thú y đề tài: Impact of coccidial infection on vaccine- and vvIBDV in lymphoid tissues of SPF chickens as detected by RT-PCR. | Acta Veterinaria Scandinavica BioMed Central Research Impact of coccidial infection on vaccine- and vvIBDV in lymphoid tissues of SPF chickens as detected by RT-PCR Susanne Kabell 1 Kurt J Handberg1 and Magne Bisgaard2 Open Access Address 1Danish Institute for Food and Veterinary Research Hang0vej 2 DK-8200 Aarhus N Denmark and 2Department of Veterinary Pathobiology The Royal Veterinary and Agricultural University 4 Stigb0jlen DK-1870 Frederiksberg C Denmark Email Susanne Kabell - ska@dfvf.dk Kurt J Handberg - kha@dfvf.dk Magne Bisgaard - Magne.Bisgaard@vetmi.kvl.dk Corresponding author Published 04 September 2006 Received 21 July 2006 J. 1 I mz 1-rri 1 z-r zn IT Accepted 04 September 2006 Acta Veterinaria Scandinavica 2006 48 17 doi 10.1186 1751-0147-48-17 This article is available from http www.actavetscand.cOm content 48 1 17 2006 Kabell et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.Org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract_ Background This study aimed at investigating a potential effect caused by coccidia on the immune response to vaccine- and very virulent infectious bursal disase virus vvIBDV in SPF chickens. Methods Two groups of three weeks old SPF chickens were vaccinated prior to inoculation with coccidia and challenge with virulent IBDV all within a period of eight days. Two control groups were similarly treated except that challenge with field virus was omitted in one group while inoculation with coccidia was omitted in the other group. Clinical signs lesions in the intestines caused by coccidia lesions in the bursa of Fabricius caused by IBDV IBDV-antibody titres and virus detection by reverse transcription polymerase chain reaction RT-PCR were compared .