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Báo cáo khoa học: " Experimental infection in calves with a specific subtype of verocytotoxin-producing Escherichia coli O157:H7 of bovine origin"

Tuyển tập các báo cáo nghiên cứu về bệnh học thý y được đăng trên tạp chí Acta Veterinaria Scandinavica cung cấp cho các bạn kiến thức về bệnh thú y đề tài: Experimental infection in calves with a specific subtype of verocytotoxin-producing Escherichia coli O157:H7 of bovine origin. | Acta Veterinaria Scandinavica BioMed Central Research Experimental infection in calves with a specific subtype of verocytotoxin-producing Escherichia coli O157 H7 of bovine origin Malin E Jonsson 1 Erik Eriksson 2 Sofia Boqvist2 3 Anne Margrete Urdahl1 and Anna Aspán2 Open Access Address National Veterinary Institute Department for Health Surveillance Oslo Norway 2National Veterinary Institute Uppsala Sweden and 3Dept of Biomedical Sciences and Veterinary Public Health Swedish University of Agricultural Sciences Uppsala Sweden Email Malin E Jonsson - malin.jonsson@vetinst.no Erik Eriksson - erik.eriksson@sva.se Sofia Boqvist-sofia.boqvist@bvf.slu.se Anne Margrete Urdahl - anne-margrete.urdahl@vetinst.no Anna Aspán - anna.aspan@sva.se Corresponding authors Published 31 October 2009 Received 17 June 2009 . J . J. 1 I mz 1-rr I Z- Accepted 31 October 2009 Acta Veterinaria Scandinavica 2009 51 43 doi l0.ll86 l75l-0l47-5l-43 This article is available from http www.actavetscand.com content 5l lM3 2009 Jonsson et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background In Sweden a particular subtype of verocytotoxin-producing Escherichia coli VTEC Ol57 H7 originally defined as being of phage type 4 and carrying two vtx2 genes has been found to cause the majority of reported human infections during the past 15 years including both sporadic cases and outbreaks. One plausible explanation for this could be that this particular subtype is better adapted to colonise cattle and thereby may be excreted in greater concentrations and for longer periods than other VTEC O1 57 H7 subtypes. Methods In an experimental study 4 calves were inoculated with 109 colony forming units cfu of strain CCUG 53931 representative of the subtype