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Báo cáo y học: " Oral malignant melanomas and other head and neck neoplasms in Danish dogs - data from the Danish Veterinary Cancer Registry"

Tuyển tập các báo cáo nghiên cứu về bệnh học thý y được đăng trên tạp chí Acta Veterinaria Scandinavica cung cấp cho các bạn kiến thức về bệnh thú y đề tài: Oral malignant melanomas and other head and neck neoplasms in Danish dogs - data from the Danish Veterinary Cancer Registry. | Acta Veterinaria Scandinavica BioMed Central Research Oral malignant melanomas and other head and neck neoplasms in Danish dogs - data from the Danish Veterinary Cancer Registry Louise B Bronden Thomas Eriksen and Annemarie T Kristensen Open Access Address Department of Small Animal Clinical Sciences Faculty of Life Sciences University of Copenhagen Dyrl gevej 16 DK-1870 Frederiksberg C Denmark Email Louise B Bronden - lobb@life.ku.dk Thomas Eriksen - ter@life.ku.dk Annemarie T Kristensen - atk@life.ku.dk Corresponding author Published 18 December 2009 Received 22 May 2009 . _ . r. J - . J. in r I r À Accepted 18 December 2009 Acta Veterinaria Scandinavica 2009 51 54 doi l0.ll86 l75l-0l47-5l -54 This article is available from http www.actavetscand.cOm content 5l l 54 2009 Bronden et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.Org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Head and neck cancers HNC are relatively common and often very serious diseases in both dogs and humans. Neoplasms originating in the head and neck region are a heterogeneous group. HNC often has an unfavourable prognosis and the proximity of the tissue structures renders extirpation of tumours with sufficient margins almost incompatible with preservation of functionality. In humans oral malignant melanoma OMM is extremely rare but represents a particular challenge since it is highly aggressive as is the canine counterpart which thus may be of interest as a spontaneous animal model. Methods Canine cases entered in the Danish Veterinary Cancer Registry DVCR from May 15th 2005 through February 29th 2008 were included in this study. Fisher s exact test was used to compare proportions of HNC in dogs and humans as well as proportions of surgically treated cases of OMM and squamous