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Báo cáo y học: "Can electrophysiological assessments of brain function be useful to the intensive care physician in daily clinical practice"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care cung cấp cho các bạn kiến thức về ngành y đề tài: Can electrophysiological assessments of brain function be useful to the intensive care physician in daily clinical practice? | Available online http ccforum.eom content 8 6 437 Commentary Can electrophysiological assessments of brain function be useful to the intensive care physician in daily clinical practice Pierre C Pandin Assistant Professor Anesthesiology and Critical Care Erasmus Hospital Free University of Brussels Brussels Belgium Corresponding author Pierre C Pandin ppandin@ulb.ac.be Published online 15 November 2004 This article is online at http ccforum.com content 8 6 437 2004 BioMed Central Ltd Related to Research by Yppărilă et al. see page 513 Critical Care 2004 8 437-439 DOI 10.1186 cc3011 Abstract Changes in electroencephalogram parameters and auditory event-related potentials induced by interruption to propofol sedation in intensive care patients provide a number of electrophysiological measures that can be used to assess neurological function accurately. Studies of electroencephalogram parameters suggest that power spectral estimation as root mean square power is more useful and precise than spectral edge frequency 95 in evaluating the functional integrity of the brain. When such parameters are used to evaluate neurological function in particular the N100 and mismatch negativity components a precise assessment of a patient s readiness to awaken from a pharmacologically induced coma such as sedation can be obtained. In terms of ease of use however it is more difficult to establish whether N100 or mismatch negativity is superior. Keywords auditory event-related potentials coma electroencephalogram evoked potentials intensive care Introduction Can electrophysiological assessments of brain function be useful to the intensive care physician in their daily clinical practice The study reported by Yppărilă and coworkers 1 sheds some light on this issue. First it should be emphasized that collaborations between intensive care physicians and electrophysiologists particularly in this highly specialized context lead to the publication of reports that have considerable scientific .