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Báo cáo khoa học: "Rapid molecular detection of methicillin-resistant Staphylococcus aureus: a cost-effective tool for infection control in critical care"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Rapid molecular detection of methicillin-resistant Staphylococcus aureus: a cost-effective tool for infection control in critical care? | Available online http ccforum.eom content 10 2 128 Commentary Rapid molecular detection of methicillin-resistant Staphylococcus aureus a cost-effective tool for infection control in critical care Marc J Struelens and Olivier Denis Department of Microbiology Université Libre de Bruxelles - Hopital Erasme Brussels Belgium Corresponding author Marc J Struelens marc.struelens@ulb.ac.be Published 14 March 2006 This article is online at http ccforum.com content 10 2 128 2006 BioMed Central Ltd Critical Care 2006 10 128 doi 10.1186 cc4855 See related research by Harbarth et al. in issue 10.1 http ccforum.com content 10 1 R25 Abstract Control strategies for methicillin-resistant Staphylococcus aureus MRSA in critical care remain debated. Timely detection of MRSA carriers is crucial to an effective isolation policy. In this issue Harbarth and colleagues report rapid MRSA screening among intensive care unit-admitted patients using a PCR assay. Preemptive isolation for all admissions until screened negative for MRSA was associated with a reduction of intensive care unit-acquired MRSA infections in one of two study units. The data provide preliminary evidence to the effectiveness of a MRSA control strategy combining rapid screening by a molecular method and preventive isolation. Further controlled studies are needed to evaluate the cost-effectiveness of this intervention. Evaluation of rapid MRSA screening and preventive isolation The study reported by Harbarth and colleagues in the previous issue of Critical Care is the first clinical investigation to evaluate the impact of a novel molecular assay for rapid screening of methicillin-resistant Staphylococcus aureus MRSA carriage in the intensive care setting 1 . The authors conducted a multistep intervention cohort study over a period of 32 months in two adult intensive care units ICUs in a university hospital. During a baseline phase screening for MRSA was performed by culture methods in high-risk patients admitted to these .