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Báo cáo y học: "Resuscitation fluid use in critically ill adults: an international cross-sectional study in 391 intensive care units"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: Resuscitation fluid use in critically ill adults: an international cross-sectional study in 391 intensive care units. | Finfer et al. Critical Care 2010 14 R185 http ccforum.eom content 14 5 R185 c CRITICAL CARE RESEARCH Open Access Resuscitation fluid use in critically ill adults an international cross-sectional study in 391 intensive care units 1 1.2 1 3 1 4 5 Simon Finfer Bette Liu Colman Taylor Rinaldo Bellomo Laurent Billot Deborah Cook Bin Du Colin McArthur6 John Myburgh1 for the SAFE TRIPS Investigators1 Abstract Introduction Recent evidence suggests that choice of fluid used for resuscitation may influence mortality in critically ill patients. Methods We conducted a cross-sectional study in 391 intensive care units across 25 countries to describe the types of fluids administered during resuscitation episodes. We used generalized estimating equations to examine the association between patient prescriber and geographic factors and the type of fluid administered classified as crystalloid colloid or blood products . Results During the 24-hour study period 1 955 of 5 274 37.1 patients received resuscitation fluid during 4 488 resuscitation episodes. The main indications for administering crystalloid or colloid were impaired perfusion 1 526 3 419 44.6 of episodes or to correct abnormal vital signs 1 189 3 419 34.8 . Overall colloid was administered to more patients 1 234 23.4 versus 782 14.8 and during more episodes 2 173 48.4 versus 1 468 32.7 than crystalloid. After adjusting for patient and prescriber characteristics practice varied significantly between countries with country being a strong independent determinant of the type of fluid prescribed. Compared to Canada where crystalloid colloid and blood products were administered in 35.5 40.6 and 28.3 of resuscitation episodes respectively odds ratios for the prescription of crystalloid in China Great Britain and New Zealand were 0.46 95 confidence interval CI 0.30 to 0.69 0.18 0.10 to 0.32 and 3.43 1.71 to 6.84 respectively odds ratios for the prescription of colloid in China Great Britain and New Zealand were 1.72 1.20 to 2.47