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Báo cáo y học: "Impact of ureido/carboxypenicillin resistance on the prognosis of ventilator-associated pneumonia due to Pseudomonas aeruginosa"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Impact of ureido/carboxypenicillin resistance on the prognosis of ventilator-associated pneumonia due to Pseudomonas aeruginosa. | Kaminski et al. Critical Care 2011 15 R112 http ccforum.eom content 15 2 R112 KS CRITICAL CARE RESEARCH Open Access Impact of ureido carboxypenicillin resistance on the prognosis of ventilator-associated pneumonia due to Pseudomonas aeruginosa f s L r I IX s m I r 1 1 1 2 IS-. c r I r I I V V r I f 2 3 h IA I I r 2 I rs D I k L 7 L s r3 4 h ỉ it vvr I I r f Z C lr ir ii 3 5 Cdineiine KdminsKi Jedn-ridnpois limsit Yondnn Dubois Jedn-Rdlpn zdEdi MdUe Gdiiousie-Oigeds Al irólion dcin3 Plici bk ĩi D 3 6 Polino Eonor7 Anno-Q l io Pil imonil8 rhrictrìnhQ AHrio9 V oc r Hon10 AUiéiien vesin Elie Azouldy Celine regei Anne Sylvie Dumenil cniistopne Adiie ives Conen Beindid AlldoucEicEe1 foi the OUTCOMEREA study gioup Abstract Introduction AltEougE Pseudomonas aeruginosa is d ledding pdtEogen responsible foi ventildtoi-dssocidted pneumonid VAP tEe excess in mortality dssocidted witE multi-iesistdnce in pdtients witE P. aeruginosa VAP PA-VAP tdKing into dccount confoundeis sucE ds tiedtment ddequdcy dnd piioi lengtn of stdy in tEe ICU bds not yet been ddequdtely estimated. Methods A totdl of 223 episodes of PA-VAP iecoided into tEe Outcomeied ddtdbdse weie evdludted. Pdtients witE uieido cdiboxy-iesistdnt P. aeruginosa PRPA weie compdied witE tbose witE uieido cdiboxy-sensitive P. aeruginosa PSPA dftei mdtcbing on duration of ICU stdy dt VAP onset dnd ddjustment foi confoundeis. Results Fdctois dssocidted witE onset of PRPA-VAP weie ds follows ddmission to tEe ICU witE septic sbocK biodd-spectium dntimiciobidls dt ddmission piioi use of uieido cdiboxypenicillin dnd colonizdtion witE PRPA before infection. Adequdte dntimiciobidl tEeidpy wds moie often deldyed in tEe PRPA gioup. Tl ie ciude ICU mortality idte dnd tEe Eospitdl mortality idte weie not different between tEe PRPA dnd tEe PSPA gioups. In multivdiidte dndlysis dftei controlling foi time in tEe ICU befoie VAP didgnosis neitEei ICU dedtE odds idtio OR 0.73 95 confidence inteivdl CI 0.32 to 1.69 P 0.46 noi Eospitdl .