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báo cáo khoa học: "Linkage disequilibrium populations between enzymatic loci in natural of Drosophila simulans"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Linkage disequilibrium populations between enzymatic loci in natural of Drosophila simulans | Génét. Sél. Evol. 1988 20 1 1-14 Linkage disequilibrium between enzymatic loci in natural populations of Drosophila simulans Catherine MONTCHAMP-MOREAU and M. KATZ Unite associée 693 du Centre National de la Recherche Scientifique Génétique des Populations Universités Paris 6 et Paris 7 75251 Paris Cedex 05 France. Summary Linkage disequilibria D between five enzymatic loci of the third chromosome Est-6 Pgm Est-C Aidox and Acph were measured in three Mediterranean populations of Drosophila simulans. Gametic frequencies were estimated by mating each sampled male with females homozygous at the five studied loci. Although our study hặd a high power of detection of linkage disequilibrium 650 to 800 gametes per sample highly polymorphic loci the frequency of significant cases is consistent with the risk a null hypothesis D 0 . Nevertheless the tighter two loci are linked the higher is the significance level of the observed disequilibrium Consequently a weak linkage disequilibrium does exist in these populations. This disequilibrium is probably caused by random genetic drift rather than by selection as significant results are not repeatable from sample to sample. Key words Drosophila simulans enzymatic polymorphism linkage disequilibrium. Resume Polymorphism enzymatique et déséquilibre gamétique dans des populations naturelles de Drosophila simulans Les déséqụilibres gamétiques D entre cinq locus enzymatiques du chromosome III Est-6 Pgm Est-C Aidox Acph ont été mesurés dans trois populations méditerranéennes de Drosophila simulans. Les frequences gamétiques ont été estimées en croisant individuellement les males captures avec des femelles homozygotes pour les cinq locus. Malgré des conditions d analyse qui assurent une puissance élevée aux tests de detection du déséquilibre gamétique 650 à 800 gametes par échantillon locus très polymorphes la proportion de cas significatifs est compatible avec les risques de premiere espèce consentis hypothèse nulle D 0 . Cependant les .