Trong năm 1980, điều tra tiết lộ rằng ống thông liên quan đến nhiễm trùng do intraluminal chứ không phải là thực dân bên ngoài xảy ra nhiều hơn nữa thường xuyên hơn đã được báo cáo trước đây (6,7). Kể từ khi phương pháp roll-đĩa mẫu nuôi cấy bề mặt bên ngoài của ống thông | 44 Catheter-Related Infections in the Critically III 1--------------1--------------1--------------r 0 20 40 00 CTC events 1000 catheter-days Figure 1. Relationship between catheter-related bloodstream infection CRBSI and catheter-tip colonization CTC utilizing data collated from 29 prospective studies on catheter-related infection. From Rijnders et al. 5 with permission Stephen o. Heard 45 Quantitative Cultures During the 1980 s investigations revealed that catheter-related infection dueto intraluminal rather than external colonization occurred much more frequently than had been previously reported 6 7 . Since the roll-plate method of aidlm lng samples only the external surface of the catheter instances of catheter-related infection or CRBSI due to luminal bacterial colonization might be missed. Severalculturing lechiii Uia have been developed zo assav bodilhe crkTiial riid luminal stirleees. One mrllvKl mvoWns immeiemg ihc r r tecli ml catheter iv Ho iiK 0sr soy biatti end Beetling lha binds with broih izv The Itiolh medm i s aerially dduind1 inechteted liiiue i dod vdar vSoZes and iniehalad for tl 2 oaurr oe AoC. An patianis why had CRBSa arew l eztn dins. dial ikairH0 iT owfowdsdofinedosihrtfuhshvld for 0 eir nvi1 iige-alluscr infection. Anvthar leaelvped i9 ry was d ydani rv ve lnc zen d ia whichacofoeterlipin aalleaad in l rd0 l as i oyi rol la anosonicaSau ill e woieibalh for Olla mmole at s i The limlh io sailtlri diluiol onto blood ager phun snn adtiiiedfon 4dhonss. d hit teclrmque a soaaalTs fofot ailrvh aand dmelloi lhti zhillinler. VFUi av yZs nltalllom or equal to lOOT atv aaaorialedieilhC sBS gndcathetes-reinSeh mlei waehadhas v Mgha-r seositizhy am1 en uqsuvalent spadfiaityfoi CRBS1 when compesedlv Iharodpliite method 1 iy dpecinl comfoeretiozmuet hegivento ydtiteptih ae ashibiotía- mpiegllalqd cathrten. Semrn 1 esa atĩr m inns hevashewnihat aamiiilk aiil amount oqi hfoss ar i i e mis- diBan adH aniahme s
