Các triệu chứng lâm sàng và dấu hiệu ở phụ nữ với hội chứng buồng trứng đa nang (PCOS) Tỷ lệ phần trăm tần số của các triệu chứng hoặc dấu hiệu Balen et al. (5) (n = 1741) (%) Franks (9) (n = 300) (%) Goldzieher (10) (n = 1079) [n (%)]% | 40 Balen Table 1 Clinical Symptoms and Signs in Women with polycystic ovary syndrome PCOS Percentage frequency of symptom or sign Number of casesa Balen et al. 5 n 1741 Franks 9 n 300 Goldzieher 10 n 1079 n Menstrual cycle disturbance Oligomenorrhea 47 52 29b n 547 Amenorrhea 28 51 n 640 Hirsutism 64 69 n 819 Obesity 35 41 n 600 Acne 27 Alopecia 6 3 Acanthosis nigricans 1 - Infertility primary secondary 20 42 74 n 596 aIn the Goldzieher study clinical details were not available for the entire 1079 women thus the number of cases that were used to determine the frequency of each symptom is stated. bIn this series any abnormal pattern of uterine bleeding was included. - Denotes feature not recorded. Table 2 Biochemical Features of Women with polycystic ovary syndrome PCOS Percentage frequency Balen et al. 5 n 1741 Franks 9 n 300 Elevated serum LH 51 Elevated serum testosterone 50 Elevated serum prolactin 7 3. POLYCYSTIC OVARIES IN THE ABSENCE OF MENSTRUAL DYSFUNCTION In the series reported by Balen et al. 5 approximately 20 were amenorrheic 50 oligomenorrheic and 30 had a regular menstrual cycle whereas the series of Franks and Goldzieher each reported 20 with a regular menstrual cycle 9 10 . Several studies have been performed to attempt to determine the prevalence of polycystic ovaries as detected by ultrasound alone in the general population and have found prevalence rates in the order of 17-33 4 11-16 The study designs and results are summarized in Table 3. All of the studies used transabdominal ultrasound for the diagnosis of polycystic ovaries except for Cresswell et al. 16 who converted to a transvaginal scan if the transabdominal picture was unclear. Table 3 The Prevalence of Polycystic Ovaries in the General Population Authors Polson et al. 11 Tayob et al. 12 Clayton et al. 13 Farquhar et al 14 Botis et al. 15 Cresswell et al. 16 Michelmore et al. 4 Study Volunteers Volunteers using Volunteers born Volunteers Volunteers
