Tỷ lệ của hội chứng chuyển hóa ở phụ nữ Ý bình thường từ 20-39 năm và trong hội chứng buồng trứng đa nang (PCOS) Ý bệnh nhân với các kiểu hình hyperandrogenic cổ điển hay rụng trứng. Xem chèn cho con số màu. | PCOS Phenotypes 127 Italian polycystic ovary syndrome PCOS patients with the classic or ovulatory hyperandrogenic phenotype. See insert for color figure. altered cardiovascular risk marker Fig. 3 11 . All of these metabolic alterations are similar but less common and generally less severe than in classic PCOS Figs 2 and 3 11 25 . Many of the differences in severity of metabolic alterations between ovulatory and classic PCOS are probably explained by differences in body weight. In fact women with ovulatory PCOS are on average leaner than patients with classic PCOS and their body weight is only slightly higher than normal women 11 . Obesity BMI 30 is present in only 8 of women with ovulatory PCOS although another 30-35 are overweight Fig. 4 . Therefore in patients with ovulatory PCOS only a mild increase of body weight is present and it is associated with less severe insulin resistance and fewer metabolic and cardiovascular consequences than those observed in women with classic PCOS. In summary patients with ovulatory PCOS are hyperandrogenic women Controls Ovulatory PCOS Classic PCOS Fig- 3- Prevalence of the finding of at least one altered cardiovascular risk factor in Italian polycystic ovary syndrome PCOS patients with classic or ovulatory hyperandrogenic phenotype. See insert for color figure. 128 Carmina Ovulatory Phenotype -Classic Phenotype Fig- 4- Distribution of body weight in Italian polycystic ovary syndrome PCOS patients with classic or ovulatory hyperandrogenic phenotype. See insert for color figure. who present many of the features of patients with classic PCOS but seem to have a less severe form of the syndrome. 4. NORMOANDROGENIC PCOS PHENOTYPE The third main phenotype of PCOS regroups patients with chronic anovulation polycystic ovaries but no clinical or biologic signs of hyperandrogenism. This phenotype has stimulated a large debate. In fact very few data exist on clinical and endocrine characteristics of this subgroup of patients and on the other
