Điểm mạnh của nghiên cứu này bao gồm phù hợp với tuổi và giới tính trong các môn học kiểm soát, sử dụng các tiêu chí vận hành TBI và "rối loạn tâm thần như tâm thần phân liệt sau TBI," phù hợp để kiểm tra các trường hợp và đối tượng kiểm soát, các cuộc phỏng vấn bệnh nhân trực tiếp | 218 TEXTBOOK OF TRAUMATIC BRAIN INJURY logical deficits with lower IQ worse verbal and visual memory and language impairment. It could not be determined of course whether these factors preceded or resulted from the TBI. Strengths of this study include matching of age and gender in control subjects use of operationalized criteria for TBI and schizophrenia-like psychosis following TBI consistent ascertainment of cases and control subjects direct patient interviews and use of informants and collection of both structural imaging and neuropsychological data although neuroimaging data were qualitative and read by different radiologists and a standard neuropsychological battery was not used . What Predicts Psychosis in Brain-Injured Individuals The preceding studies are the most recent and perhaps most methodologically sound attempts at clarifying the characteristics of injury that place someone at risk for developing psychosis after brain injury. A variety of other studies have looked at other specific factors that may contribute to the development of posttraumatic psychosis including location and extent of injury and genetic vulnerability. Location of Injury Accumulated evidence suggests that injuries to the left hemisphere and to the temporal lobes may be most closely associated with risk of posttraumatic psychosis Davison and Bagley 1969 . As noted Sachdev et al. 2001 found that those with a TBI who developed psychosis had more CT scan evidence of brain damage especially in the left temporal and parietal regions than those who did not develop a psychosis though this did not survive Bonferroni correction. In a logistic regression model only left temporal damage significantly predicted the occurrence of psychosis after TBI. In an earlier study Hillbom 1960 found that 40 of individuals with posttraumatic psychosis had temporal lobe injuries a significantly higher occurrence than in those with nonpsychotic psychiatric disturbance. Of the group with psychosis 63 had .
