Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài:Skeletal Plasmacytoma: Progression of disease and impact of local treatment; an analysis of SEER database | Journal of Hematology Oncology BioMed Central Research Skeletal Plasmacytoma Progression of disease and impact of local treatment an analysis of SEER database Muhammad Umar Jawad and Sean P Scully Open Access Address Departments of Orthopaedics University of Miami Miller School of Medicine 1400 NW 12th Avenue Miami FL 33136 USA Email Muhammad Umar Jawad - mjawad@ Sean P Scully - sscully@ Corresponding author Published 24 September 2009 Received 14 August 2009 Accepted 24 September 2009 Journal of Hematology Oncology 2009 2 41 doi 1756-8722-2-41 This article is available from http content 2 1 41 2009 Jawad and Scully licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Previous reports suggest an as yet unidentifiable subset of patients with plasmacytoma will progress to myeloma. The current study sought to establish the risk of developing myeloma and determine the prognostic factors affecting the progression of disease. Methods Patients with plasmacytoma diagnosed between 1973 and 2005 were identified in the SEER database ll64 patients . Patient demographics and clinical characteristics treatment s cause of death and survival were extracted. Kaplan-Meier log-rank and Cox regression were used to analyze prognostic factors. Results The five year survival among patients initially diagnosed with plasmacytoma that later progressed to multiple myeloma and those initially diagnosed with multiple myeloma were almost identical 25 and 23 respectively . Five year survival for patients with plasmacytoma that did not progress to multiple myeloma was significantly better 72 . Age 60 years was the only factor that correlated with progression of disease p . Discussion
