Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài:Acute dyspnoea and single tracheal localisation of mantle cell lymphoma | lanotto et al. Journal of Hematology Oncology 2010 3 34 http content 3 1 34 LETTER TO THE EDITOR JOURNAL OF HEMATOLOGY ONCOLOGY Open Access Acute dyspnoea and single tracheal localisation of mantle cell lymphoma 1 1 1 2 3 Jean-Christophe lanotto Adrian Tempescul Jean-Richard Eveillard Norbert André Frederic Morel Isabelle Quintin-Roué4 Christian Berthou 1 Abstract Background Mantle cell lymphoma is a lymphoid entity characterized by adenopathy blood and bone marrow involment which only recurrent mucosal localisation is the lymphomatoid polyposis. Few other mucosal infiltrations have been already reported. Results We report here the first case of a unique tracheal localisation of mantle cell lymphoma at presentation of the disease. The presence of classical t 11 14 q13 q32 confirmed the diagnosis of mantle cell lymphoma by eliminating MALT or cancer localisation. Conclusion This case illustrates the necessity to ensure the diagnosis of mucosal lymphoma versus MCL since these diseases need different treatment regimens and prognoses. To the Editor We report here an unusual case of a tracheal localisation of mantle cell lymphoma MCL . The patient was 75-years-old and hospitalized for dyspnoea dysphonia and stridor evolving from 3 months. No superficial tumoural syndrome was observed and the patient did not express B-symptoms. The CT-scan showed the presence of an endotracheal tumour of two centimetres under the glottis and two mediastinal centimetric lymph nodes. No other localisations were found. The bronchial endoscopy showed an obstructive vascularised tumour Figure 1 and the stomach endoscopy was negative. The pneumologist took multiple biopsies and used both laser and endotracheal prothesis to treat the dyspnoea. The anatomo-pathologist identified a massive proliferation of medium to large cells with abundant and clear cytoplasm round or oval nuclei. Mitosis were observed. Those cells were CD20 bcl-2 lymphoid cells with no lymphoepithelial .
