Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài:A patient presenting with a perivascular epithelioid cell tumor in the broad ligament: a case report | Ross et al. Journal of Medical Case Reports 2011 5 383 http content 5 1 383 JOURNAL OF MEDICAL CASE REPORTS CASE REPORT Open Access A patient presenting with a perivascular epithelioid cell tumor in the broad ligament a case report í I - I r D ff Cii i 2 rs r I I I I - 3 ft fl r I I C I I_I r 4 n I III n r 4 Claire Ross Sunita Sharma onsy Louca Michelle Scurr Andrew Hayes and Ian Judson Abstract Introduction Perivascular epithelioid cell tumors are a family of rare mesenchymal tumors composed of histologically and immunohistochemically distinctive perivascular epithelioid cells. They can originate in any visceral organ or soft tissue and include a range of lesions such as angiomyolipoma clear cell sugar tumor of the lung lymphangioleiomyomatosis and clear cell myomelanocytic tumors of the falciparum ligament ligament teres. Due to their rarity and varied sites and presentation management of these tumors remains highly challenging. Case Presentation A 46-year-old para 2 Caucasian woman initially presented to the general surgeons at our hospital in North West London with abdominal pain. Laparoscopy revealed a right broad ligament hematoma which was thought to be iatrogenic in origin from insertion of the Veress needle at the time of surgery and was managed conservatively. Upon her re-presentation two months later with severe pain ultrasound scanning revealed the hematoma had increased in size and she underwent a total abdominal hysterectomy and bilateral salpingo-oophorectomy. Histology results from necrotic tissue from the hematoma led to a diagnosis of perivascular epithelioid cell tumor. She was then referred to a tertiary oncology center where she underwent several further operations in an attempt to debulk the tumor for symptomatic relief of her pain with limited success. She is now taking the immunosuppressive drug sirolimus which has produced a modest reduction in tumor size. She is now 47 months on from initial presentation. .
