báo cáo khoa học: "A rapidly progressing Pancoast syndrome due to pulmonary mucormycosis: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: A rapidly progressing Pancoast syndrome due to pulmonary mucormycosis: a case report | Bansal et al. Journal of Medical Case Reports 2011 5 388 http content 5 1 388 JOURNAL OF MEDICAL CASE REPORTS CASE REPORT Open Access A rapidly progressing Pancoast syndrome due to pulmonary mucormycosis a case report 1 2 34 2 Meghana Bansal Sara R Martin Stacy A Rudnicki Kim M Hiatt and Eduardo Mireles-Cabodevila Abstract Introduction Pancoast syndrome is characterized by Horner syndrome shoulder pain radiating down the arm compression of the brachial blood vessels and in long-standing cases atrophy of the arm and hand muscles. It is most commonly associated with lung carcinoma but rarely is seen with certain infections. Case presentation We present the case of a 51-year-old Caucasian man who had acute myeloid leukemia and who developed a rapidly fulminating pneumonia along with signs and symptoms of acute brachial plexopathy and left Horner syndrome. Also a purpuric plaque developed over his left chest wall and progressed to skin necrosis. The skin biopsy and bronchoalveolar lavage showed a Rhizopus species leading to a diagnosis of mucormycosis. This is a rare case of pneumonia due to mucormycosis associated with acute Pancoast syndrome. Conclusions According to our review of the literature only a few infectious agents have been reported to be associated with Pancoast syndrome. We found only three case reports of mucormycosis associated with acute Pancoast syndrome. Clinicians should consider mucormycosis in their differential diagnosis in a patient with pulmonary lesions and chest wall invasion with or without neurological symptoms especially in the setting of neutropenia or other immunosuppressed conditions. It is important to recognize this condition early in order to target therapy and interventions. Introduction Pancoast syndrome is most commonly associated with a primary lung carcinoma and rarely with metastatic malignancies and certain infections including mucormycosis. It is characterized by Horner syndrome shoulder pain .

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