Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: A case of polyarteritis nodosa limited to the right calf muscles, fascia, and skin: a case report | FW JOURNALOF MEDICAL Ur Case reports A case of polyarteritis nodosa limited to the right calf muscles fascia and skin a case report Ahmed et al. BioMed Central Ahmed et al. Journal of Medical Case Reports 2011 5 450 http content 5 1 450 12 September 2011 Ahmed et al. Journal of Medical Case Reports 2011 5 450 http content 5 1 450 WV journalof medical l rCASE REPORTS CASE REPORT Open Access A case of polyarteritis nodosa limited to the right calf muscles fascia and skin a case report Saad Ahmed1 Joanne Kitchen1 Samuel Hamilton2 Francesca Brett3 and David Kane1 Abstract Introduction Limited polyarteritis nodosa is a rare benign disease that usually responds well to systemic corticosteroid treatment. We report a case limited to calf muscles fascia and skin treated with local corticosteroid therapy directed to the affected areas by ultrasound guidance. Case presentation A 36-year-old Caucasian woman presented with a 10-month history of progressive right calf pain and swelling which were unresponsive to treatment with non-steroidal anti-inflammatory drugs and physiotherapy. An examination revealed a swollen tender right calf with indurated overlying skin. Laboratory investigations showed an erythrocyte sedimentation rate of 24 mm hour and a C-reactive protein of 15 mg dl. Full blood count renal profile and creatinine kinase level were normal. A full autoantibody screen and hepatitis B and C serology results were negative. A chest X-ray was unremarkable. Magnetic resonance imaging of the right leg revealed increased signal intensity in T2-weighted images and this was suggestive of extensive inflammatory changes of the gastrocnemius muscle and to a lesser extent the soleus muscle. There were marked inflammatory changes throughout the gastrocnemius muscle and the subcutaneous tissue circumferentially around the right lower leg. A biopsy of affected skin muscle and fascia showed histopathological features consistent .
