Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Triple malignancy in a single patient including a cervical carcinoma, a basal cell carcinoma of the skin and a neuroendocrine carcinoma from an unknown primary site: A case report and review of the literature | Mesmoudi et al. Journal of Medical Case Reports 2011 5 462 http content 5 1 462 WV journalof medical l rCASE REPORTS CASE REPORT Open Access Triple malignancy in a single patient including a cervical carcinoma a basal cell carcinoma of the skin and a neuroendocrine carcinoma from an unknown primary site A case report and review of the literature Mohamed Mesmoudi Saber Boutayeb Tarik Mahfoud Rachid Aasab Nabil Ismaili Meryem Glaoui and Hassan Errihani Abstract Introduction The occurrence of multiple primary cancers is rare. Only a few cases and patient reviews of an association of triple malignancy have been reported. Case presentation We report here a case of a 78-year-old Moroccan woman presenting initially with a synchronous double malignancy the first in her cervix and the second in her skin. Our patient was treated with radiation therapy for both tumors and remained in good control for 17 years when she developed a metastatic disease from a neuroendocrine carcinoma of an unknown primary site. Conclusions Although the association of multiple primary cancers can be considered a rare occurrence improving survival in cancer patients has made this situation more frequent. Introduction The increasing effectiveness of cancer therapies and the improvement of diagnostic tools have led to better survival rates among cancer patients. This situation has made the problem of developing subsequent primary tumors more frequent. In the literature the prevalence of multiple primary cancer MPC is estimated between and and the incidence is increasing with age 1 . According to the Surveillance Epidemiology and End Results cancer registries of the National Cancer Institute cancer survivors had a 14 higher risk of developing a new malignancy than would have been expected in the general population. Females had a slightly higher relative risk than males for all subsequent cancers combined and the most implicated sites were breast colon lung and .
