Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Pseudoclavibacter-like subcutaneous infection: a case report | Lemaitre et al. Journal of Medical Case Reports 2011 5 468 http content 5 1 468 JOURNALOF medical Ur Case REPORTS CASE REPORT Open Access Pseudoclavibacter-like subcutaneous infection a case report Frangois Lemaitre1 Andreas Stein2 Didier Raoult1 3 and Michel Drancourt1 3 Abstract Background Arthrobacter-like organisms including Pseudoclavibacter organisms have rarely been documented as being responsible for infection in humans. Case presentation An 81-year-old French man developed a subcutaneous infection despite antibiotic treatment combining clindamycin and metronidazole for chronic wound infection. A skin biopsy showed numerous polymorphonuclear cells and no bacteria but a subcutaneous swab yielded numerous polymorphonuclear cells a few Gram-positive cocci Gram-negative cocci and Gram-positive rods. The Gram-positive rod sequence exhibited 99 sequence similarity with uncultured Pseudoclavibacter sp. GenBank EF419350 and 99 sequence similarity with uncultured Pseudoclavibacter sp. GenBank EF419347 . The genetic data and unique peptide profile of this Pseudoclavibacter-like isolate determined by matrix-assisted laser desorption ionization-time of flight mass spectrometry underscored its uniqueness. Conclusions Pseudoclavibacter-like organisms are identifiable in cutaneous and subcutaneous infections in humans. Keywords Pseudoclavibacter 16S rRNA gene MALDI-TOF identification skin infection Background Pseudoclavibacter is an emerging bacterial genus created a few years ago to accommodate environmental Brevi-bacterium organisms 1 . Indeed Arthrobacter-like bacteria have rarely been isolated in patients and a Pseudoclavibacter organism has been reported to be isolated only once from an aortic valve of a 74-year-old man 2 . Case presentation An 81-year-old French man was admitted to our hospital for erysipelas of the right leg. The patient had suddenly developed this infection despite antibiotic treatment combining clindamycin and .
