báo cáo khoa học: " Inflammatory pseudotumors of the kidney and the lung presenting as immunoglobulin G4related disease: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Inflammatory pseudotumors of the kidney and the lung presenting as immunoglobulin G4related disease: a case report | Nishikawa et al. Journal of Medical Case Reports 2011 5 480 http content 5 1 480 JOURNAL OF MEDICAL CASE REPORTS CASE REPORT Open Access Inflammatory pseudotumors of the kidney and the lung presenting as immunoglobulin G4-related disease a case report Genya Nishikawa Kogenta Nakamura Yoshiaki Yamada Takahiko Yoshizawa Yoshiharu Kato Remi Katsuda Kenji Zennami Motoi Tobiume Shigeyuki Aoki Tomohiro Taki and Nobuaki Honda Abstract Introduction It has been reported that immunoglobulin G4-related systemic disease can spread to nearly every organ and often presents as an inflammatory mass or masses at those sites. In the kidney this disease is often diagnosed after a radical or partial nephrectomy following the discovery of an inflammatory mass which is often suspected to be a malignant tumor. Here we present a rare case of inflammatory pseudotumors of the kidney and the lung presenting as immunoglobulin G4-related disease which were diagnosed by computed tomography-guided biopsies. Case presentation A 54-year-old Japanese man was referred to our hospital with suspected bilateral renal cancer multiple lung metastases and autoimmune pancreatitis. His serum immunoglobulin G4 level was high. We used computed tomography-guided biopsies and histopathological examinations of the biopsied specimens to diagnose the tumors as immunoglobulin G4-related bilateral renal and lung inflammatory pseudotumors. Our patient was treated with oral prednisolone and after one month of treatment contrast-enhanced computed tomography demonstrated a general improvement as noted by a reduction in size of the masses. Conclusion Renal masses that are formed due to immunoglobulin G4-related disease require comprehensive diagnosis to prevent unnecessary surgical resections from being performed. Further consideration should be paid to immunoglobulin G4-related diseases in the future. Introduction Patients with autoimmune pancreatitis often exhibit high serum immunoglobulin .

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