Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài:Delay in diagnosis of generalized miliary tuberculosis with osseo-articular involvement: a case report | Rodrigo and Atukorala Journal of Medical Case Reports 2011 5 512 http content 5 1 512 JOURNAL OF MEDICAL CASE REPORTS CASE REPORT Open Access Delay in diagnosis of generalized miliary tuberculosis with osseo-articular involvement a case report Chaturaka Rodrigo and Inoshi Atukorala Abstract Introduction Diagnosis of atypical tuberculosis is difficult. Therefore it is important that physicians are aware of rare presentations of tuberculosis to avoid diagnostic delays. Case presentation We present the case of a 17-year-old Sri Lankan man who presented to our facility with an ill-defined large induration over the skin of his left buttock and thigh. A cause could not be found despite extensive investigations. He also complained of chronic knee pain but this was not investigated further at the time due to spontaneous resolution. Three years later his knee disease flared up again with pain swelling and restriction of movement. A synovial biopsy was suggestive of tuberculosis. He was started on antituberculosis therapy to which he responded well. Our patient was asymptomatic two months after completion of therapy without any subsequent flare-ups. A chest roentgenogram taken on his second presentation showed evidence of tuberculosis sequelae in his lungs. The most likely diagnosis for the buttock and thigh swelling when considering the entire clinical picture is a tuberculous abscess. The constellation of skin and skeletal symptoms and pulmonary tuberculosis is a rare occurrence in an immunocompetent individual but cases have been reported. Conclusions This case demonstrates the different presentations and the diagnostic difficulties posed by atypical manifestations of tuberculosis. It also demonstrates the value of maintaining a high degree of suspicion in endemic areas even in the absence of microbiological evidence. Introduction The incidence of tuberculosis TB was assumed to be increasing in parallel with the HIV epidemic. However latest .
