Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Severe community-acquired adenovirus pneumonia in an immunocompetent 44-year-old woman: a case report and review of the literature. | JOURNALOF MEDICAL Ltcase reports Severe community-acquired adenovirus pneumonia in an immunocompetent 44-year-old woman a case report and review of the literature Clark et al. BioMed Central Clark et al. Journal of Medical Case Reports 2011 5 259 http content 5 1 259 30 June 2011 Clark et al. Journal of Medical Case Reports 2011 5 259 http content 5 1 259 JOURNALOF medical Ur Case REPORTS CASE REPORT Open Access Severe community-acquired adenovirus pneumonia in an immunocompetent 44-year-old woman a case report and review of the literature Tristan W Clark Daniel H Fleet and Martin J Wiselka Abstract Introduction This case report describes a rare condition community-acquired adenovirus pneumonia in an immunocompetent adult. The diagnosis was achieved by using a multiplex real-time reverse transcriptase polymerase chain reaction RT-PCR assay and highlights the usefulness of these novel molecular diagnostic techniques in patients hospitalized with acute respiratory illness. We also performed a literature search for previously published cases and present a summary of the clinical laboratory and radiological features of this condition. Case presentation A 44-year-old immunocompetent Caucasian woman was admitted to our hospital with an acute febrile respiratory illness associated with a rash. Her blood tests were non-specifically abnormal and tests for bacterial pathogens were negative. Her condition rapidly deteriorated while she was in our hospital and required mechanical ventilation and inotropic support. A multiplex real-time RT-PCR assay performed on respiratory specimens to detect respiratory viruses was negative for influenza but positive for adenovirus DNA. The patient recovered on supportive treatment and antibiotics were stopped after 5 days. Conclusions Community-acquired adenovirus pneumonia in immunocompetent adult civilians presents as a nonspecific acute febrile respiratory illness followed by the .