Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Octreotide-induced thrombocytopenia: a case report. | Rashidi and Rizvi Journal of Medical Case Reports 2011 5 286 http content 5 1 286 JOURNAL OF MEDICAL CASE REPORTS CASE REPORT Open Access Octreotide-induced thrombocytopenia a case report Armin Rashidi1 and Nahid Rizvi2 Abstract Introduction Thrombocytopenia is an extremely rare complication of octreotide therapy and can be life threatening in the setting of esophageal variceal bleeding. We report a case of octreotide-induced reversible thrombocytopenia in a 54-year-old Caucasian man with alcohol-induced cirrhosis and upper gastrointestinal bleeding. Case presentation Our patient s platelet count dropped from 155 000 mm3 upon admission to 77 000 mm3 a few hours after initiation of octreotide therapy and stayed low until the drug s administration was discontinued. Significant recovery was achieved quickly after discontinuation of octreotide. Conclusions Thrombocytopenia is a rare but potentially serious side effect of octreotide therapy and may complicate esophageal variceal bleeding. Physicians should be vigilant in identifying this potentially serious condition. Introduction Drug-induced thrombocytopenia can complicate esophageal variceal bleeding. Octreotide is a standard treatment in patients with portal hypertension presenting with upper gastrointestinal bleeding. Octreotide-induced thrombocytopenia is a rare condition that has been reported in only two previous cases 1 2 . Another case is reported herein. Case presentation A 54-year-old Caucasian man with a medical history of alcoholic liver disease and grade I esophageal varices presented to our hospital with a one-day history of hematemesis and light-headedness. The patient did not have any comorbidities and his last alcoholic beverage consumption was three days before admission. His initial vital signs revealed blood pressure of 111 73 mmHg heart rate of 129 beats minute respiratory rate of 22 breaths minute and 100 oxygen saturation on room air. His physical examination revealed
