Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Osteogenic sarcoma of the breast arising in a cystosarcoma phyllodes: a case report and review of the literature. | Singhal et al. Journal of Medical Case Reports 2011 5 293 http content 5 1 293 JOURNAL OF MEDICAL CASE REPORTS CASE REPORT Open Access Osteogenic sarcoma of the breast arising in a cystosarcoma phyllodes a case report and review of the literature Vinay Singhal1 Chintamani2 and John M Cosgrove1 Abstract Introduction Primary tumors of the breast containing bone and cartilage are extremely rare and an osteogenic sarcoma arising from a cystosarcoma phyllodes is exceptional. Case presentation A 40-year-old Indian woman presented with a breast mass which was diagnosed as osteosarcoma of the breast on biopsy. Our patient was treated with a simple mastectomy after excluding the presence of skeletal primary and extra-mammary metastases. Final pathology showed a cystosarcoma phyllodes with signs of osteogenic sarcoma. Conclusion Although osteogenic sarcomas of the breast are rare they need to be distinguished from carcinosarcomas and metaplastic carcinomas as the management of the two differ. Introduction Carcinoma is the most common malignancy of the breast. Sarcomas form a minority of breast neoplasms. Extra-skeletal osteosarcomas have been reported in many tissues of the body including thyroid gland kidneys bladder colon heart testes and penis. In the breast it either occurs as a metaplastic differentiation of a pre-existing benign or malignant tumor or de novo from normal breast tissue. We present a case of osteogenic sarcoma arising in a cystosarcoma phyllodes of the breast. Case presentation A 40-year-old Indian woman presented to our outpatient department with complaints of a lump in her left breast noted four months prior to presentation. The lump gradually increased in size and was non-tender. There was no history of nipple discharge. The patient denied any hormonal therapy or family history of breast disease. A physical examination found our patient to be obese and in no acute distress. A breast examination showed her left breast to be .
