Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Upper cervical intramedullary spinal metastasis of ovarian carcinoma: a case report and review of the literature. | Miranpuri et al. Journal of Medical Case Reports 2011 5 311 http content 5 1 311 JOURNALOF medical Ur Case REPORTS CASE REPORT Open Access Upper cervical intramedullary spinal metastasis of ovarian carcinoma a case report and review of the literature Amrendra S Miranpuri1 Sharad Rajpal1 M Shahriar Salamat2 and John S Kuo1 Abstract Introduction Currently there is no generalized approach to treating patients with intra-medullary spinal metastasis. High cervical spinal cord lesions can be particularly challenging cases and may even be considered inoperable by some. Case report We present what is to the best of our knowledge the first reported case of ovarian carcinoma managed primarily with surgery in a 65-year-old Caucasian woman metastasizing to the upper cervical spinal cord we also review the relevant literature and discuss management strategies. Conclusions Due to improving systemic cancer therapies patients with cancer now often survive longer and are more likely to develop central nervous system metastases. Therefore neurosurgical oncologists are often challenged with difficult decisions about how to surgically manage these patients. We recommend individualized multidisciplinary management based on patient functional status the need for definitive diagnosis for possible additional adjuvant therapies and consideration of extent of systemic disease impacting on desirable quality and length of survival. Introduction Whereas lung and breast cancer represent the most frequently occurring spinal intra-medullary metastatic neoplasms other solid tumors such as ovarian carcinoma can also rarely metastasize to the spinal cord. On imaging studies the differential diagnoses for intra-medul-lary spinal lesions can include gliomas and vascular malformations but rare spinal infections such as tuberculosis can still be seen in some parts of the world 1 2 . The clinical presentation can range from minor neurological symptoms to major symptoms that .
