Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Ganglioneuroblastoma of the posterior mediastinum: a case report. | Fatimi et al. Journal of Medical Case Reports 2011 5 322 http content 5 1 322 JOURNALOF medical case reports CASE REPORT Open Access Ganglioneuroblastoma of the posterior mediastinum a case report Saulat H Fatimi1 Samira A Bawany2 and Awais Ashfaq2 Abstract Introduction Ganglioneuroblastoma is a rare peripheral neuroblastic tumor that is derived from developing neuronal cells of the sympathetic nervous system and is found mostly but not exclusively in babies and young children. Case presentation To the best of our knowledge there have been no previously reported cases of ganglioneuroblastoma of the mediastinum from Pakistan. We present a case of ganglioneuroblastoma in an eight-year-old Pakistani Sindhi boy incidentally found to have a large posterior mediastinal mass that on biopsy initially looked like ganglioneuroma. He underwent successful excision of the mediastinal mass and remained stable post-operatively. Final pathology findings showed a ganglioneuroblastoma. He has remained free of symptoms on long-term follow-up. Conclusions The rarity of this tumor along with its almost exclusive occurrence in the pediatric population necessitates a thorough investigation of patients presenting with a symptomatic mass. Introduction Ganglioneuroblastoma is a rare variety of peripheral neuro-blastic tumor neuroblastoma that can arise anywhere along the sympathetic nervous system. It occurs almost exclusively in the pediatric population with some reported cases in the adult population. It is the third most common childhood malignancy after leukemia and brain tumors and is the commonest solid extracranial tumor among children 1 . Its true global incidence however is unknown. According to the Surveillance Epidemiology and End Results SEER Registry maintained by the National Cancer Institute the annual incidence of neuroblastoma is per 1 000 000 population in the USA 2 . Of these cases no statistics regarding the subtype of ganglioneuroblastoma
