Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Immune reconstitution inflammatory syndrome associated with acquired immunodeficiency syndrome-related . | Pal et al. Journal of Medical Case Reports 2011 5 327 http content 5 1 327 JOURNALOF medical Ur Case REPORTS CASE REPORT Open Access Immune reconstitution inflammatory syndrome associated with acquired immunodeficiency syndrome-related gastrointestinal limited Kaposi s sarcoma presenting as acute intestinal obstruction a case report Jyotirmoy Pal1 Ankit Shrivastav2 Hari Shankar Pathak3 and Dipendra Kumar Sarkar4 Abstract Introduction Immune reconstitution inflammatory syndrome during anti-retroviral treatment of acquired immunodeficiency syndrome AIDS -associated gastrointestinal Kaposi s sarcoma has rarely been reported. Case Presentation A 36-year-old Asian Indian male newly diagnosed with AIDS and treatment naive was started on highly active antiretroviral therapy HAART . He developed acute intestinal obstruction after four weeks of therapy. A laparotomy was done with excision and adhesiolysis leading to relief of symptoms. A histology report revealed the lesion to be Kaposi s sarcoma. Our patient was diagnosed to be having immune reconstitution inflammatory syndrome associated with AIDS-associated gastrointestinal limited Kaposi s sarcoma which presented as acute intestinal obstruction. Our patient was treated with paclitaxel post-operatively and HAART was continued. Our patient responded to therapy. Conclusion Immune reconstitution inflammatory syndrome involving Kaposi s sarcoma may occur in HAART-naive individuals with AIDS-related Kaposi s sarcoma. Gastrointestinal Kaposi s sarcoma may present with sudden increase in size or inflammation leading to acute intestinal obstruction. This does not indicate failure of HAART or a need for changes in anti-retroviral regimen. Introduction Kaposi s sarcoma KS remains the most common tumor in individuals infected with human immunodeficiency virus HIV and is associated with significant morbidity and mortality. Highly active anti-retroviral therapy HAART for acquired immunodeficiency syndrome
