Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Peritoneal dissemination of prostate cancer due to laparoscopic radical prostatectomy: a case report. | JOURNALOF MEDICAL LJtcase reports Peritoneal dissemination of prostate cancer due to laparoscopic radical prostatectomy a case report Hiyama et al. Hiyama et al. Journal of Medical Case Reports 2011 5 355 http content 5Z1 355 5 August 2011 BioMed Central Hiyama et al. Journal of Medical Case Reports 2011 5 355 http content 5 1 355 JOURNAL OF MEDICAL CASE REPORTS CASE REPORT Open Access Peritoneal dissemination of prostate cancer due to laparoscopic radical prostatectomy a case report 1 1 1 1 1 2 Yoshiki Hiyama Hiroshi Kitamura Satoshi Takahashi Naoya Masumori Tetsuya Shindo Mitsuhiro Tsujiwaki Tomoko Mitsuhashi2 Tadashi Hasegawa2 and Taiji Tsukamoto1 Abstract Introduction Peritoneal dissemination with no further metastases of prostate cancer is very rare with only three cases reported in the available literature. We report the first case of iatrogenic peritoneal dissemination due to laparoscopic radical prostatectomy. Case Presentation A 59-year-old Japanese man underwent laparoscopic radical prostatectomy for clinical T2bN0M0 prostate cancer and the pathological diagnosis was pT3aN0 Gleason 3 4 adenocarcinoma with a negative surgical margin. Salvage radiation therapy was performed since his serum prostate-specific antigen remained at a measurable value. After the radiation he underwent castration followed by combined androgen blockade with estramustine phosphate and dexamethasone as each treatment was effective for only a few months to a year. Nine years after the laparoscopic radical prostatectomy computed tomography revealed a peritoneal tumor although no other organ metastasis had been identified until then. He died six months after the appearance of peritoneal metastasis. An autopsy demonstrated peritoneal dissemination of the prostate cancer without any other metastasis. Conclusion Physicians should take into account metastasis to unexpected sites. Furthermore we suggest that meticulous care be taken not
