Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Emerging Applications of Bacterial Spores in Nanobiotechnology | Journal of Nanobiotechnology BioMed Central Review Open Access Emerging Applications of Bacterial Spores in Nanobiotechnology Ezio Ricca1 and Simon M Cutting 2 Address 1Dipartimento di Fisiologia Generale ed Ambientale Università Federico II Napoli Italy and 2School of Biological Sciences Royal Holloway University of London Egham UK Email Ezio Ricca - ericca@ Simon M Cutting - Corresponding author Published 15 December 2003 Received 26 November 2003 Journal of Nanobiotechnology 2003 1 6 Accepted 15 December 2003 This article is available from http content 1 1 6 2003 Ricca and Cutting licensee BioMed Central Ltd. This is an Open Access article verbatim copying and redistribution of this article are permitted in all media for any purpose provided this notice is preserved along with the article s original URL. Abstract Bacterial spores are robust and dormant life forms with formidable resistance properties in part attributable to the multiple layers of protein that encase the spore in a protective and flexible shield. The coat has a number of features pertinent to the emerging field of nanobiotechnology including self-assembling protomers and the capacity for engineering and delivery of foreign molecules. This review gives an account of recent progress describing the use of the spore and specifically the spore coat as a vehicle for heterologous antigen presentation and protective immunization vaccination . As interest in the spore coat increases it seems likely that they will be exploited further for drug and enzyme delivery as well as a source of novel self-assembling proteins. Background Nanostructured surfaces exhibit unique physical and chemical properties that can be exploited for many important technological applications to produce molecular structures and systems for the assembly within the nanometre size range. Nanotechnology not only can produce surfaces with novel functionality but also new devices that
